assuming you mean for a relationship-smoking, stupidity, uptight, bad hygiene...i could go on for hours, i'm very picky haha.
personaly i like a females that smoke. a girl who can toke is a girl i can poke.
as for turn offs:
hairy upper lips
& bad breath
Cancer sticks, and if she can't hold an intelligent conversation. I have dated a dumb girl before, and it was really painful talking to her. I had to explain every topic I brought up. It was horrible.