After checking spark plugs and coils making sure everything is good. You can take note of your coils and swap them to different cylinders and see if the misfire follows the coils. If not do the same thing with the spark plugs.
Check connections, and check your plugs. Might as well replace the plugs since they're relatively cheap. I am running RS3 Plugs/Coils and the car runs great *knock on wood*
Don't shotgun parts when you haven't pulled the codes. You have the same symptoms after changing the coils so they are not the cause. At this mileage I would suspect carbon buildup is causing the misfire.