What GPU are you running? I ultimately ran into issues with 1440p UW on my 5700XT, bought a 6950XT and it's been worlds better.
I definitely still use multiple displays -- one's an UW 1080p, and then two 24" 1080p displays in portrait. Portrait monitors are underrated.
6800XT. I'm one of those weird guys that actually likes to have semi-nice graphics when playing shooters, so 144+ can be a struggle at times.