The Meanwell PS are pretty stout. It seems like the firmware ramps up the fan pretty early on, so I figure if heat gets to be an issue it will just shut off anyways. I don’t like using an enclosure, mostly because I find it a PITA more than anything.If you buy an OE Prusa enclosure they have you mount the PS on the outside. Probably just to be on the safe side.
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My printed solid enclosure that has everything inside it has been great but I have not done any prints longer than 5-6 hours in it. Will it shorten the lifespan of the PS? Possibly, they don’t like heat. Am I worried enough to move it outside the enclosure, no.